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Toll-like receptors are critical for clearance of Brucella and play different roles in development of adaptive immunity following aerosol challenge in mice

Brucella spp. cause undulant fever in humans and brucellosis in variety of other animals. Both innate and adaptive immunity have been shown to be important in controlling Brucella infection. Toll-like receptors (TLRs) represent a group of pattern recognition receptors that play critical roles in t...

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Principais autores: Jianwu ePei, Xicheng eDing, Yaping eFan, Allison Rice Ficht, Thomas A Ficht
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012-09-01
coleção:Frontiers in Cellular and Infection Microbiology
Assuntos:
Adaptive Immunity
Brucella
MyD88
innate immunity
TLR
aerosol infection
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00115/full
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