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Mycobacterium tuberculosis Rv0309 Dampens the Inflammatory Response and Enhances Mycobacterial Survival

To reveal functions of novel Mycobacterium tuberculosis (M. tb) proteins responsible for modulating host innate immunity is essential to elucidation of mycobacterial pathogenesis. In this study, we aimed to identify the role of a putative protein Rv0309 encoded within RD8 of M. tb genome in inhibiti...

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Main Authors: Yongchong Peng, Xiaojie Zhu, Lin Gao, Jieru Wang, Han Liu, Tingting Zhu, Yifan Zhu, Xin Tang, Changmin Hu, Xi Chen, Huanchun Chen, Yingyu Chen, Aizhen Guo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
mycobacterium tuberculosis
Rv0309
BCG_RS01790
mycobacterium bovis BCG
inflammation
pathogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.829410/full
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