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Genomic and phenotypic insight into Clostridioides difficile RT027 isolates from China reveals diverse virulence associated with clinical symptoms

Clostridioides difficile (C. difficile) ribotype 027 (RT027) has caused severe outbreaks in North America and Europe over the past 20 years. However, RT027 infections are rare in Asia, particularly in China, with limited severe cases. To clarify its molecular and phenotypic features, we investigated...

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Main Authors: Wenjia Wang, Shan Lin, Yun Luo, Chunhong Shao, Qikai Shi, Jing Shao, Yu Chen, Hui Hu, Shuangshuang Wan, Xiaojun Song, Dazhi Jin, Yan Jin
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2026-12-01
Series:Emerging Microbes and Infections
Subjects:
Clostridioides difficile
ribotype 027 (RT027)
virulence
next generation sequencing (NGS)
toxin
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2026.2637287
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