Cell-Permeable Succinate Increases Mitochondrial Membrane Potential and Glycolysis in Leigh Syndrome Patient Fibroblasts

Mitochondrial disorders represent a large group of severe genetic disorders mainly impacting organ systems with high energy requirements. Leigh syndrome (LS) is a classic example of a mitochondrial disorder resulting from pathogenic mutations that disrupt oxidative phosphorylation capacities. Curren...

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Hlavní autoři:	Ajibola B. Bakare, Raj R. Rao, Shilpa Iyer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-08-01
Edice:	Cells
Témata:	leigh syndrome succinate prodrug glycolysis TCA cycle mitochondrial respiration
On-line přístup:	https://www.mdpi.com/2073-4409/10/9/2255
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