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Interferon regulatory factor 3 mediates effective antiviral responses to human coronavirus 229E and OC43 infection

Interferon regulatory factors (IRFs) are key elements of antiviral innate responses that regulate the transcription of interferons (IFNs) and IFN-stimulated genes (ISGs). While the sensitivity of human coronaviruses to IFNs has been characterized, antiviral roles of IRFs during human coronavirus inf...

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Autores principales: Joseph K. Sampson Duncan, Danyang Xu, Maria Licursi, Michael A. Joyce, Holly A. Saffran, Kaiwen Liu, Jin Gohda, D. Lorne Tyrrell, Yasushi Kawaguchi, Kensuke Hirasawa
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2023-05-01
Colección:Frontiers in Immunology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fimmu.2023.930086/full
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