IRE1α-XBP1 but not PERK inhibition exerts anti-tumor activity in osteosarcoma
Abstract Osteosarcoma (OS) is the most common primary malignant bone tumor. However, the therapeutic results of the advanced cases at the first visit were still extremely poor. Therefore, more effective therapeutic options based on molecular profiling of OS are needed. In this study, we investigated...
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| Principais autores: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer
2021-11-01
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| coleção: | Discover Oncology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1007/s12672-021-00453-2 |
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