Characterizing PSMA heterogeneity in prostate cancer and identifying clinically actionable tumor associated antigens in PSMA negative cases

Abstract Prostate-specific membrane antigen (PSMA)-targeted theranostics have profoundly reshaped prostate cancer (PCa) management. However, patterns of PSMA expression heterogeneity and the identification of alternative targets for PSMA-negative cases remain insufficiently understood. To address th...

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Detalhes bibliográficos

Principais autores:	Yelin Mulati, Qi Shen, Yuxuan Tian, Yuke Chen, Kaifeng Yao, Wei Yu, Yunpeng Cui, Xuedong Shi, Zhisong He, Qian Zhang, Yu Fan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-07-01
Colecção:	Scientific Reports
Assuntos:	Prostate cancer Prostate-specific membrane antigen Heterogeneity Tumor-associated antigen
Acesso em linha:	https://doi.org/10.1038/s41598-025-06393-z
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