Group I metabotropic glutamate receptors differentially modulate excitatory transmission across interneuron types in the human cortex

IntroductionGroup I metabotropic glutamate receptors (mGluRs) play a critical role in regulating neuronal excitability, synaptic strength, and cortical network activity. Although their physiological functions and involvement in neurological disorders are well established, direct experimental evidenc...

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Main Authors:	Joanna Grace Sandle, Gábor Molnár, Martin Tóth, Katalin Ágnes Kocsis, Éva Adrienn Csajbók, Pál Barzó, Karri Lamsa, Gábor Tamás
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2026-02-01
Series:	Frontiers in Synaptic Neuroscience
Subjects:	brain slice electrophysiology fast-spiking interneurons human neocortex interneurons synaptic modulation type I metabotropic glutamate receptors
Online Access:	https://www.frontiersin.org/articles/10.3389/fnsyn.2026.1766413/full
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