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The role of SDF_1α/CXCR4 axis in non-antibody mediated TRALI in cardiac surgery patients

Abstract Background Acute lung injury (ALI) after extracorporeal circulation can originate from multiple causes, including transfusion. Despite improvements in blood safety policy, transfusion-related lung injury (TRALI) continues to occur, suggesting an incomplete understanding of its pathogenesis....

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Autori principali: Mickael Vourc’h, Enora Ferron, Cécile Poulain, Gaëlle David, Christelle Volteau, Jérémie Poschmann, Martin Braud, Regis Josien, Bertrand Rozec, Jose A Villadangos, Christelle Retiere, Karim Asehnoune
Natura: Artigo
Lingua:Inglês
Pubblicazione: SpringerOpen 2026-07-01
Serie:Intensive Care Medicine Experimental
Soggetti:
Cardiac surgery
Transfusion
Red blood cell
Respiratory failure
CXCL12
SDF_1α
Accesso online:https://doi.org/10.1186/s40635-026-00919-z
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