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Ginseng flower total saponin extract alleviates type 1 diabetes mellitus-associated liver injury via PI3K/AKT/HIF-1α signaling pathway

Background: Type 1 diabetes mellitus (T1DM) induces liver complications via oxidative stress and inflammation, with limited therapeutic options targeting these mechanisms. Ginseng flower total saponin extract (GFTS), a multi-component natural product, shows metabolic regulatory potential but remains...

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Main Authors: Lian-Hua Han, Minqi Jin, Xin Qi, Zheng Nan, Chengbi Cui
Format: Artigo
Language:Inglês
Published: Elsevier 2025-10-01
Series:Journal of Agriculture and Food Research
Subjects:
Ginseng flower total saponin
T1DM
Network pharmacology
PI3K/AKT/HIF-1α signalling pathway
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2666154325005691
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