Systemic Immune Modulation Alters Local Bone Regeneration in a Delayed Treatment Composite Model of Non-Union Extremity Trauma

Bone non-unions resulting from severe traumatic injuries pose significant clinical challenges, and the biological factors that drive progression towards and healing from these injuries are still not well understood. Recently, a dysregulated systemic immune response following musculoskeletal trauma h...

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Bibliografske podrobnosti

Principais autores:	Casey E. Vantucci, Tyler Guyer, Kelly Leguineche, Paramita Chatterjee, Angela Lin, Kylie E. Nash, Molly Ann Hastings, Travis Fulton, Clinton T. Smith, Drishti Maniar, David A. Frey Rubio, Kaya Peterson, Julia Andraca Harrer, Nick J. Willett, Krishnendu Roy, Robert E. Guldberg
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-07-01
Serija:	Frontiers in Surgery
Teme:	immune dysregulation non-union musculoskeletal trauma MDSCs S100A8/A9
Online dostop:	https://www.frontiersin.org/articles/10.3389/fsurg.2022.934773/full
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