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The role and mechanisms of macrophage polarization and hepatocyte pyroptosis in acute liver failure

Acute liver failure (ALF) is a severe liver disease caused by disruptions in the body’s immune microenvironment. In the early stages of ALF, Kupffer cells (KCs) become depleted and recruit monocytes derived from the bone marrow or abdomen to replace the depleted macrophages entering the liver. These...

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Hlavní autoři: Dan Xie, Shi Ouyang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2023-10-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1279264/full
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