Bioengineered ovary reconstructs follicle-like structures in a mouse model of chemotherapy-induced premature ovarian failure

Abstract Background We investigated the applicability of human decellularized ovarian scaffold (HDOS) to create an artificial ovary for preserving germ cells and forming follicular-like structures in a mouse chemotherapy-induced premature ovarian failure (chemo-POF) model after seeding stromal cells...

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Autori principali:	Fatemeh Abedi Ghehi, Farideh Eivazkhani, Leila Mirzaeian, Naeimeh Sadat Abtahi, Hussein Eimani, Somayeh Tavana, Rouhollah Fathi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-11-01
Serie:	Stem Cell Research & Therapy
Soggetti:	Premature ovarian failure Chemotherapy Germ cells Human ovarian scaffold Transplantation Artificial ovary
Accesso online:	https://doi.org/10.1186/s13287-025-04823-3
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