Influence of pH on the cytotoxic activity of inositol hexakisphosphate (IP6) in prostate cancer

Objectives: In the present study, we investigated whether the pH of IP6 could influence its anti-tumoral activity in vitro. Methods: PC-3 cells were exposed to IP6 at pH 5, pH 7 and pH 12 and we evaluated the metabolic activity (WST-1 assay), cell proliferation (cell count), cell cycle distribution...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Blandine eBetton, Philippe O. Gannon, Ismaël Hervé eKoumakpayi, Jean-Simon eDiallo, Anne-Marie eMes-Masson, Fred eSaad
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2011-10-01
סדרה:	Frontiers in Oncology
נושאים:	Cell Cycle phytochemicals inositol hexakisphosphate (IP6) metabolic activity PC-3 cells
גישה מקוונת:	http://journal.frontiersin.org/Journal/10.3389/fonc.2011.00040/full
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