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Enhancement of Dissolving Capacity and Reducing Gastric Mucosa Irritation by Complex Formation of Resibufogenin with β-Cyclodextrin or 2-Hydroxypropyl-β-cyclodextrin

Resibufogenin (RBG) is a natural medicinal ingredient with promising cardiac protection and antitumor activity. However, poor solubility and severe gastric mucosa irritation restrict its application in the pharmaceutical field. In this study, the inclusion complex of RBG with β-cyclodextrin (β-CD) a...

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Principais autores: Nan Liu, Huan-Ping Chen, Zi-Meng Yang, Ming-Yu Xia, Dong Wang, Ling-He Zang, Dong-Chun Liu
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-05-01
Series:Molecules
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Acceso en liña:https://www.mdpi.com/1420-3049/27/10/3213
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