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Effect of gastrointestinal digestion on the stability and cytotoxicity of conventional and pegylated liposomes encapsulated with stigmasterol and its esters

Abstract Conventional and PEGylated liposomes encapsulated with stigmasterol and its esters were prepared, and their stability and cytotoxicity during in vitro gastrointestinal digestion were determined. The release of stigmasterol and its oxidation products were analyzed using GC-FID. The cytotoxic...

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Principais autores: Magdalena Rudzińska, Anna Grygier, Anna Olejnik, Katarzyna Kowalska, Joanna Igielska-Kalwat, Dominik Kmiecik, Katarzyna Cieślik-Boczula
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-09-01
Colecção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-025-17473-5
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