Hepatitis C Virus Infection Induces Autophagy as a Prosurvival Mechanism to Alleviate Hepatic ER-Stress Response

Hepatitis C virus (HCV) infection frequently leads to chronic liver disease, liver cirrhosis and hepatocellular carcinoma (HCC). The molecular mechanisms by which HCV infection leads to chronic liver disease and HCC are not well understood. The infection cycle of HCV is initiated by the attachment a...

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Detalhes bibliográficos

Principais autores:	Srikanta Dash, Srinivas Chava, Yucel Aydin, Partha K. Chandra, Pauline Ferraris, Weina Chen, Luis A. Balart, Tong Wu, Robert F. Garry
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2016-05-01
Colecção:	Viruses
Assuntos:	Hepatitis C virus (HCV) Endoplasmic reticulum stress (ER-stress) Unfolded protein response (UPR) Autophagy Chaperon-mediated autophagy (CMA) Interferon (IFN) Interferon-alpha receptor-1 (IFNAR1) chronic liver disease (CLD) Hepatocellular carcinoma (HCC)
Acesso em linha:	http://www.mdpi.com/1999-4915/8/5/150
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