Dynamic screening initiation using 16 plasma protein biomarkers with polygenic risk and PLCOm2012: a precision prevention framework for lung cancer

Abstract Background low-dose computed tomography (LDCT) screening strategies for lung cancer are primarily targeted at high-risk groups based on smoking history and age, leading to over-screening of low-risk individuals while delaying timely detection in high-risk groups. This study aimed to develop...

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Detalhes bibliográficos

Principais autores:	Runchen Wang, Zhiming Ye, Qixia Wang, Rong Xu, Yi Feng, Na Zhao, Yun Yan, Yulin Zhao, Xuanzhuang Lu, Xiangyuan Zheng, Jianqi Zheng, Hongsheng Deng, Ran Zhong, Rui Gao, Jie Li, Wenhua Liang, Jianxing He, Hengrui Liang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	Journal of Translational Medicine
Assuntos:	Lung cancer Proteomics PRS Risk advancement period Precision oncology
Acesso em linha:	https://doi.org/10.1186/s12967-025-07468-1
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