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Identification of Fangjihuangqi Decoction as a late-stage autophagy inhibitor with an adjuvant anti-tumor effect against non-small cell lung cancer

Abstract Background Clinically, although chemotherapy is one of the most commonly used methods of treating tumors, chemotherapeutic drugs can induce autophagic flux and increase tumor cell resistance, leading to drug tolerance. Therefore, theoretically, inhibiting autophagy may improve the efficacy...

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Principais autores: Qiugu Chen, Yuan Liao, Yujiao Liu, Yue Song, Junbo Jiang, Zhen zhang, Anqi Li, Mengyi zheng, Xiaoyi Chen, Tingxiu Zhao, Jiangyong Gu, Yuhui Tan, Xiaoyi Liu, Yanjun Jiang, Kun Wang, Hua Yi, Jianyong Xiao, Shan Hu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-06-01
Serier:Chinese Medicine
Fag:
Fangjihuangqi decoction
Autophagy inhibition
Sensitization
Cisplatin
Paclitaxel
Online adgang:https://doi.org/10.1186/s13020-023-00770-4
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