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Comprehensive profiling of retroviral integration sites using target enrichment methods from historical koala samples without an assembled reference genome

Background. Retroviral integration into the host germline results in permanent viral colonization of vertebrate genomes. The koala retrovirus (KoRV) is currently invading the germline of the koala (Phascolarctos cinereus) and provides a unique opportunity for studying retroviral endogenization. Prev...

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Huvudupphov: Pin Cui, Ulrike Löber, David E. Alquezar-Planas, Yasuko Ishida, Alexandre Courtiol, Peter Timms, Rebecca N. Johnson, Dorina Lenz, Kristofer M. Helgen, Alfred L. Roca, Stefanie Hartman, Alex D. Greenwood
Materialtyp: Artigo
Språk:Inglês
Utgiven: PeerJ Inc. 2016-03-01
Serie:PeerJ
Ämnen:
Integration sites
Retroviral endogenization
KoRV
Target enrichment
Clustering
Länkar:https://peerj.com/articles/1847.pdf
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