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Safety of Continuing Trastuzumab Despite Mild Cardiotoxicity

Objectives: This study sought to evaluate the safety of continuing trastuzumab in patients with human epidermal growth factor receptor–positive breast cancer who developed mild cardiotoxicity. Background: Cardiotoxicity is the most common dose-limiting toxicity associated with trastuzumab. Current s...

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Main Authors: Darryl P. Leong, MBBS, MPH, MBiostat, PhD, Tammy Cosman, PhD, Muhammad M. Alhussein, MD, Nidhi Kumar Tyagi, MBChB, Sarah Karampatos, MS, Carly C. Barron, MD, MS, Douglas Wright, MD, Vikas Tandon, MD, Patrick Magloire, MD, Philip Joseph, MD, David Conen, MD, MPH, P.J. Devereaux, MD, PhD, Peter M. Ellis, MBBS, MMed, PhD, Som D. Mukherjee, MD, MS, Sukhbinder Dhesy-Thind, MD, MS
Format: Artigo
Language:Inglês
Published: Elsevier 2019-09-01
Series:JACC. CardioOncology
Subjects:
breast cancer
cardiomyopathy
HER2
trastuzumab
Online Access:http://www.sciencedirect.com/science/article/pii/S2666087319300055
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