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Compartment-specific tumor-infiltrating immune cells and prognosis in breast cancer

Summary: Breast cancer immune response is important to patient outcome, but the prognostic interaction between tissue-infiltrating immune cell (TIIC) types is not well-characterized. We evaluated the associations between CD8+, FOXP3+, CD20+, and CD163+ TIICs and breast cancer-specific survival (BCSS...

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Principais autores: Aaron J. Bernstein, Renske Keeman, Amber N. Hurson, Fiona M. Blows, Manjeet K. Bolla, Jodi L. Miller, Roger L. Milne, Hugo Horlings, Alexandra J. van den Broek, Clara Bodelon, James M. Hodge, Alpa V. Patel, Lauren R. Teras, Federico Canzian, Rudolf Kaaks, Hermann Brenner, Ben Schöttker, Sabine Behrens, Jenny Chang-Claude, Tabea Maurer, Nadia Obi, Fergus J. Couch, H. Raza Ali, Carlos Caldas, Irene Andrulis, Gord Glendon, Anna Marie Mulligan, Wilma Mesker, Agnes Jager, Annette Heemskerk-Gerritsen, Peter Devilee, Scott M. Lawrence, Jolanta Lissowska, Karun Mutreja, Thomas Ahearn, Stephen Chanock, Maire A. Duggan, Diana Eccles, J. Louise Jones, Will Tapper, Antoinette Hollestelle, Maartje Hooning, John Martens, Carolien H.M. van Deurzen, Angela Cox, Simon S. Cross, Mikael Hartman, Jingmei Li, Thomas C. Putti, Ute Hamann, Muhammad Rashid, Ania Jakubowska, Nicki Camp, Melissa H. Cessna, Amy Berrington de Gonzalez, Katarzyna Bialkowska, Jacek Gronwald, Jan Lubiński, Siddhartha Yadav, Pietro Lio, Douglas F. Easton, Mustapha Abubakar, Montse Garcia-Closas, Paul D.P. Pharoah, Marjanka K. Schmidt
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2026-02-01
Series:iScience
Assuntos:
Oncology
Immunology
Artificial intelligence
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2589004226001343
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