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Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death.

Protein Tyrosine Phosphatase localized to the Mitochondrion 1 (PTPMT1) is a dual specificity phosphatase exclusively localized to the mitochondria, and has recently been shown to be a critical component in the cardiolipin biosynthetic pathway. The downregulation of PTPMT1 in pancreatic beta cells ha...

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Bibliografische gegevens
Hoofdauteurs: Natalie M Niemi, Nathan J Lanning, Laura M Westrate, Jeffrey P MacKeigan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2013-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC3542197?pdf=render
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