High expression of the checkpoint molecule PD-1 on regulatory and helper CD4+ T cells in metastatic breast cancer patients with poor prognosis

Background: Recurrence and metastasis are common in patients of breast cancer even after chemotherapy and radiotherapy. This recurrence may occur due to the emergence of immunoregulatory T (Treg) cells and the immune checkpoint molecules such as programmed cell death protein 1 (PD-1) which are known...

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Autori principali:	Mohamed Esmail, Mohamed Attia, Sameh Abd-Alaziz, Sabry El-Naggar, Mohamed Salem
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	The Egyptian Association for Cancer Research (EACR) 2020-04-01
Serie:	Egyptian Journal of Cancer and Biomedical Research
Soggetti:	Breast Cancer, CD4+ T cells, T regulatory cells Checkpoint molecules Programmed cell death protein PD-1, Flow cytometry
Accesso online:	https://jcbr.journals.ekb.eg/article_93035_677090436ef6cd637efaf5847f011253.pdf
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