Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins.

SH3 domains are peptide recognition modules that mediate the assembly of diverse biological complexes. We scanned billions of phage-displayed peptides to map the binding specificities of the SH3 domain family in the budding yeast, Saccharomyces cerevisiae. Although most of the SH3 domains fall into...

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Bibliografiske detaljer

Principais autores:	Raffi Tonikian, Xiaofeng Xin, Christopher P Toret, David Gfeller, Christiane Landgraf, Simona Panni, Serena Paoluzi, Luisa Castagnoli, Bridget Currell, Somasekar Seshagiri, Haiyuan Yu, Barbara Winsor, Marc Vidal, Mark B Gerstein, Gary D Bader, Rudolf Volkmer, Gianni Cesareni, David G Drubin, Philip M Kim, Sachdev S Sidhu, Charles Boone
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2009-10-01
Serier:	PLoS Biology
Online adgang:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19841731/?tool=EBI
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