The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1β by Human Cytomegalovirus through Inhibition of NF-kB Activity

Interleukin-1β (IL-1β) is a key effector of the inflammasome complex in response to pathogens and danger signals. Although it is well known that assembly of the inflammasome triggers proteolytic cleavage of the biologically inactive precursor pro-IL-1β into its mature secreted form, t...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Matteo Biolatti, Valentina Dell’Oste, Sara Scutera, Francesca Gugliesi, Gloria Griffante, Marco De Andrea, Tiziana Musso, Santo Landolfo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2018-10-01
coleção:	Viruses
Assuntos:	human cytomegalovirus (HCMV) pp65 inflammasome interleukin-1β (IL-1β) caspase-8
Acesso em linha:	http://www.mdpi.com/1999-4915/10/10/567
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!