Primed mesenchymal stem cells attenuate schistosomiasis fibrosis by enhancing macrophage subset switching and efferocytosis via Itgb2-Rac1 axis
Abstract The pathological hallmark of schistosomiasis is egg-induced granulomatous inflammation and the subsequent fibrosis in the liver; and mesenchymal stem cells have been explored for the treatment of schistosomiasis fibrosis. However, the underlying mechanisms are largely unknown. We demonstrat...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2026-02-01
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| Col·lecció: | Cell Death Discovery |
| Accés en línia: | https://doi.org/10.1038/s41420-026-02947-w |
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