High-grade serous ovarian carcinoma organoids as models of chromosomal instability

High-grade serous ovarian carcinoma (HGSOC) is the most genomically complex cancer, characterized by ubiquitous TP53 mutation, profound chromosomal instability, and heterogeneity. The mutational processes driving chromosomal instability in HGSOC can be distinguished by specific copy number signature...

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書誌詳細

主要な著者:	Maria Vias, Lena Morrill Gavarró, Carolin M Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton
フォーマット:	Artigo
言語:	Inglês
出版事項:	eLife Sciences Publications Ltd 2023-05-01
シリーズ:	eLife
主題:	organoids high-grade serous ovarian cancer chromosomal instability
オンライン･アクセス:	https://elifesciences.org/articles/83867
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