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Crosstalk between corepressor NRIP1 and cAMP signaling on adipocyte thermogenic programming

Objectives: Nuclear receptor interacting protein 1 (NRIP1) suppresses energy expenditure via repression of nuclear receptors, and its depletion markedly elevates uncoupled respiration in mouse and human adipocytes. We tested whether NRIP1 deficient adipocytes implanted into obese mice would enhance...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Emmanouela Tsagkaraki, Adilson Guilherme, Sarah M. Nicoloro, Mark Kelly, Lawrence M. Lifshitz, Hui Wang, Kyounghee Min, Leslie A. Rowland, Kaltinaitis B. Santos, Nicole Wetoska, Randall H. Friedline, Stacy A. Maitland, Min Chen, Lee S. Weinstein, Scot A. Wolfe, Jason K. Kim, Michael P. Czech
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2023-10-01
Schriftenreihe:Molecular Metabolism
Schlagworte:
Diabetes
Obesity
Adipose tissue
Adrenergic signaling
CRISPR
Implant
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S221287782300114X
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