Global assessment of partial artemisinin resistance: multicenter trial across Kenya, Peru, and Thailand in patients with uncomplicated Plasmodium falciparum malaria

Objectives: Artemisinin-resistant Plasmodium falciparum challenges the effectiveness of all artemisinin-based combination therapies. Methods: We conducted a clinical study in Peru, Kenya, and Thailand between June 2013 and November 2015 in subjects treated with three standard doses of artesunate fol...

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Autori principali:	Ben Andagalu, Edward Smith, Salomon Durand, Hugo O. Valdivia, Irene Onyango, Michele Spring, Vanachayangkul Pattaraporn, G. Christian Baldeviano, Elazia Majid, Sabaithip Sriwichai, James Cummings, Lorena Tapia, Hosea Akala, Panita Gosi, Cesar Cabezas, Dennis Juma, Saowaluk Wongararunkochakorn, Moises Sihuincha, Chaiyaporn Chaisatit, Lorna Chebon-Bore, Worachet Kuntawunginn, Alaina Halbach, Chanikarn Kodchakorn, Chatchadaporn Thamnurak, Chantida Praditpol, Piyaporn Saingam, Kimberly A. Edgel, David Saunders, Agnes Cheruiyot, Ilin Chuang, Ekaterina Milgotina, Paula Fernandes, Andres G. Lescano, Nonlawat Boonyalai, Edwin Kamau, Brett M. Forshey, Stephanie Cinkovich, Delia Bethell, Krisada Jongsakul, Mark Fukuda
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-10-01
Serie:	International Journal of Infectious Diseases
Soggetti:	Malaria Artemisinin Resistance K13 mutations
Accesso online:	http://www.sciencedirect.com/science/article/pii/S120197122500195X
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