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Predictive value of BRCA1, ERCC1, ATP7B, PKM2, TOPOI, TOPΟ-IIA, TOPOIIB and C-MYC genes in patients with small cell lung cancer (SCLC) who received first line therapy with cisplatin and etoposide.

<h4>Background</h4>The aim of the study was to evaluate the predictive value of genes involved in the action of cisplatin-etoposide in Small Cell Lung Cancer (SCLC).<h4>Methods</h4>184 SCLC patients' primary tumour samples were analyzed for ERCCI, BRCA1, ATP7B, PKM2 TOPOI, TOPOIIA, TOPOIIB and C-MYC...

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Библиографические подробности
Главные авторы: Niki Karachaliou, Chara Papadaki, Eleni Lagoudaki, Maria Trypaki, Maria Sfakianaki, Anastasios Koutsopoulos, Dimitris Mavroudis, Efstathios Stathopoulos, Vassilis Georgoulias, John Souglakos
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2013-01-01
Серии:PLoS ONE
Online-ссылка:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0074611&type=printable
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