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Isovalerylspiramycin I alleviates liver injury and liver fibrosis by targeting the nucleotide-binding protein 2 (NUBP2)-vascular non-inflammatory molecule-1 (VNN1) pathway

Liver fibrosis is a vital cause of morbidity in patients with liver diseases and developing novel anti-fibrotic drugs is imperative. Isovalerylspiramycin I (ISP I) as a major component of carrimycin applied to upper respiratory infections, was first found to possess anti-fibrotic potential. The pres...

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Principais autores: Na Zhang, Weixiao Niu, Weiping Niu, Yiming Li, Simin Guo, Yang Li, Weiqing He, Hongwei He
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-03-01
coleção:Journal of Pharmaceutical Analysis
Assuntos:
Liver fibrosis
Isovalerylspiramycin I
Carrimycin
Nucleotide-binding protein 2
Vascular non-inflammatory molecule-1
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S209517792400145X
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