Pyruvate kinase deficiency and PKLR gene mutations: Insights from molecular dynamics simulation analysis

Pyruvate kinase deficiency is a rare hereditary erythrocyte enzyme disease caused by mutations in the pyruvate kinase liver and red blood cell gene. The clinical presentations of pyruvate kinase deficiency are significantly heterogeneous, ranging from just mild anemia to hemolytic crisis or even dea...

Descrición completa

Detalles Bibliográficos

Principais autores:	Yang Wang, Jiaqi Liu, Tao Liu, Xizhou An, Lan Huang, Jiacheng Li, Yongjie Zhang, Yan Xiang, Li Xiao, Weijia Yi, Jiebin Qin, Lili Liu, Cuilan Wang, Jie Yu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2024-03-01
Series:	Heliyon
Assuntos:	Mutation Pyruvate kinase deficiency Pyruvate kinase Molecular dynamics simulation
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2405844024023995
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!