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Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model

BackgroundZhilong Huoxue Tongyu Capsule (ZLHXTY) has been used in clinical treatment of vascular diseases caused by hypertension over 20 years. However, the specific mechanisms by ZLHXTY alleviate hypertensive retinopathy (HR) needs to be further explored.Materials and methodsHR mouse model was esta...

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Principais autores: Jiao Wu, Wen Xie, Yucen Xie, Maryam Mazhar, Junguo Duan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-05-01
coleção:Frontiers in Pharmacology
Assuntos:
ZhiLong HuoXue TongYu Capsule
traditional Chinese medicine
hypertensive retinopathy
NLRP3 inflammasome
pyroptosis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2025.1573693/full
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