Non‐Additive Effects of Combined NOX1/4 Inhibition and Calcimimetic Treatment on a Rat Model of Chronic Kidney Disease‐Mineral and Bone Disorder (CKD‐MBD)

ABSTRACT Chronic kidney disease‐mineral and bone disorder (CKD‐MBD) increases cardiovascular calcification and skeletal fragility in part by increasing systemic oxidative stress and disrupting mineral homeostasis through secondary hyperparathyroidism. We hypothesized that treatments to reduce reacti...

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Hlavní autoři:	John G Damrath, Neal X Chen, Corinne E Metzger, Shruthi Srinivasan, Kalisha O'Neill, Annabel Biruete, Keith G Avin, Joseph M Wallace, Matthew R Allen, Sharon M Moe
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2022-03-01
Edice:	JBMR Plus
Témata:	BONE MICROARCHITECTURE CALCIMIMETICS CHRONIC KIDNEY DISEASE‐MINERAL AND BONE DISORDER OXIDATIVE STRESS VASCULAR CALCIFICATION
On-line přístup:	https://doi.org/10.1002/jbm4.10600
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