Efficacy of lytic bacteriophages isolated from sewage-treatment plants in Mbarara district, Uganda against ciprofloxacin-resistant Salmonella Typhi in a mice infection model

Abstract Background Resistance to antibiotics often leads to therapeutic failure and mortality, especially in resource-limited countries including Uganda. This necessitates the search for efficacious and safe alternatives. The study determined the in vivo efficacy of isolated lytic bacteriophages fr...

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Hauptverfasser:	Phoebe N. Bindyo, Ntulume Ibrahim, Jackim Nabona, Godswill J. Udom, Jesca L. Nakavuma
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-04-01
Schriftenreihe:	BMC Infectious Diseases
Schlagworte:	Bacteriophage therapy Multi-drug resistant species Lytic bacteriophages Sewage Ciprofloxacin-resistant S. Typhi
Online-Zugang:	https://doi.org/10.1186/s12879-026-13248-z
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