Protection of rat primary hippocampal cultures from Aβ cytotoxicity by pro-inflammatory molecules is mediated by astrocytes
The brain of Alzheimer's disease patients shows abundant dystrophic neurites in close proximity to fibrillar β-amyloid (Aβ) plaques, and activated glial cells. We evaluated the influence of pro-inflammatory molecules (LPS + IFN-γ) on Aβ1–42 neurotoxicity. 2 μM Aβ1–42 induced apoptosis of hippocampal...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2005-06-01
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| coleção: | Neurobiology of Disease |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0969996105000069 |
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