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Mechanobiologically-optimized non-resorbable artificial bone for patient-matched scaffold-guided bone regeneration

Abstract Scaffold-guided bone regeneration is poised to revolutionize the management of critical-sized bone defects. However, translation into clinical practice has been hampered by the focus on bioresorbable scaffolds where the rate of degradation needs to match the rate of bone formation and metal...

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Hauptverfasser: Jonathan R. Clark, D. S. Abdullah Al Maruf, Eva Tomaskovic-Crook, Kai Cheng, William T. Lewin, Hai Xin, Boyang Wan, Jiongyu Ren, Chi Wu, Hedi V. Kruse, Daniel K. Lawrence, Innes Wise, Aditi Gupta, Maria A. Woodruff, Maryam Alsadat Rad, David Leinkram, Timothy Manzie, Krishnan Parthasarthi, James Wykes, Tsu-Hui Hubert Low, Dale Howes, Catriona Froggatt, Ruta Gupta, Gordon Wallace, Qing Li, David R. McKenzie, Jeremy M. Crook
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-10-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-025-64466-z
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