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Repurposing FDA-Approved Drugs as Hendra Virus RNA-Dependent RNA Polymerase Inhibitors: A Comprehensive Computational Drug Discovery Approach

Hendra virus (HeV) is a highly pathogenic zoonotic paramyxovirus that poses a serious threat to human and equine health, yet no approved antivirals or vaccines currently exist. RNA-dependent RNA polymerase (RdRp) of Hendra virus represents a critical and attractive target for antiviral drug developm...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Anjana C. Lalu, Varun Thachan Kundil, Bristow Ben Joseph, Radul R. Dev, Amritha Thaikkad, Suhail Subair, Rajesh Raju, Abhithaj Jayanandan
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2025-12-01
Rangatū:Viruses
Ngā marau:
hendra virus
RNA-dependent RNA polymerase
FDA-approved drugs
molecular dynamics
Urunga tuihono:https://www.mdpi.com/1999-4915/17/12/1613
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