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Chlorpyrifos Toxicity in Mouse Cultured Cerebellar Granule Neurons at Different Stages of Development: Additive Effect on Glutamate-Induced Excitotoxicity

Objective: Chlorpyrifos (CPF) is a neurotoxic organophosphorus (OP) insecticide. Its mechanism of action includes oxidative stress, excitotoxicity, and inhibition of the acetylcholinesterase enzyme (AChE). The aim of the present study is to investigate CPF toxicity in mature and immature cerebell...

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Autores principales: Nahid Amani, Maliheh Soodi, Bahram Daraei, Abolfazl Dashti
Formato: Artigo
Lenguaje:Inglês
Publicado: Royan Institute (ACECR), Tehran 2016-09-01
Colección:Cell Journal
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Acceso en línea:http://celljournal.org/web/journal/article/6140/download
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