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Nanoparticle-Based Dry Powder Inhaler Containing Ciprofloxacin for Enhanced Targeted Antibacterial Therapy

<b>Background</b>: Ciprofloxacin (CIP) is a poorly water-soluble fluoroquinolone-type antibiotic that can be useful in the treatment of lung infections. When the drugs are delivered directly to the lungs, a smaller dosage is needed to achieve the desired effect compared to the oral administration. M...

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Main Authors: Petra Party, Márk László Klement, Bianca Maria Gaudio, Milena Sorrenti, Rita Ambrus
Format: Artigo
Language:Inglês
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
Subjects:
ciprofloxacin
nanosuspension
dry powder inhaler
wet milling
spray drying
aerodynamic characterization
Online Access:https://www.mdpi.com/1999-4923/17/4/486
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