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Enhanced Levels of Peroxisome-Derived H<sub>2</sub>O<sub>2</sub> Do Not Induce Pexophagy but Impair Autophagic Flux in HEK-293 and HeLa Cells

Peroxisomes are functionally specialized organelles that harbor multiple hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-producing and -degrading enzymes. Given that this oxidant functions as a major redox signaling agent, peroxisomes have the intrinsic ability to mediate and modulate H<sub>2</sub>O<...

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Autores principales: Hongli Li, Celien Lismont, Cláudio F. Costa, Mohamed A. F. Hussein, Myriam Baes, Marc Fransen
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2023-03-01
Colección:Antioxidants
Materias:
peroxisomes
hydrogen peroxide
pexophagy
autophagy
oxidative stress
mKeima
Acceso en línea:https://www.mdpi.com/2076-3921/12/3/613
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