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Bioinformatics analysis of adhesin-binding potential and ADME/Tox profile of anti-Helicobacter pylori peptides derived from wheat germ proteins

Anti-adhesive activity of wheat germ-derived peptides, which is considered as one of the promising strategies for preventing Helicobacter pylori infection, was investigated. The underlying mechanism of anti-adhesive action was due to peptides acting as receptor analogues and binding to H. pylori adh...

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Main Authors: Chi Dang, Ogadimma Okagu, Xiaohong Sun, Chibuike C. Udenigwe
Format: Artigo
Language:Inglês
Published: Elsevier 2022-06-01
Series:Heliyon
Subjects:
Bioactive peptides
Anti-adhesive activity
Biostability
Binding affinity
Bioinformatics
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022009173
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