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Reconstituted TAD-size chromatin fibers feature heterogeneous nucleosome clusters

Abstract Large topologically associated domains (TADs) contain irregularly spaced nucleosome clutches, and interactions between such clutches are thought to aid the compaction of these domains. Here, we reconstituted TAD-sized chromatin fibers containing hundreds of nucleosomes on native source huma...

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Autors principals: Nikolay Korolev, Anatoly Zinchenko, Aghil Soman, Qinming Chen, Sook Yi Wong, Nikolay V. Berezhnoy, Rajib Basak, Johan R. C. van der Maarel, John van Noort, Lars Nordenskiöld
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2022-09-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-022-19471-3
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