Rgnef regulates bone mass through the activation of RhoA and Rac1
Abstract Rho guanine nucleotide exchange factor (Rgnef/p190RhoGEF), a RhoA-specific guanine nucleotide exchange factor, has been implicated in cancer and amyotrophic lateral sclerosis, but little is known about its role in bone. Here we investigate the roles of Rgnef in bone metabolism using Rgnef-d...
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| Principais autores: | , , , , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Nature Publishing Group
2026-01-01
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| 丛编: | Experimental and Molecular Medicine |
| 在线阅读: | https://doi.org/10.1038/s12276-025-01631-w |
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