Microglial heterogeneity in the ischemic stroke mouse brain of both sexes

Abstract Background Ischemic stroke elicits a complex and sustained immune response in the brain. Immunomodulatory treatments have long held promise for improving stroke outcomes, yet none have succeeded in the clinical setting. This lack of success is largely due to our incomplete understanding of...

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Hlavní autoři:	Ángela del Águila, Ran Zhang, Xinyuan Yu, Lihong Dang, Feng Xu, Jin Zhang, Vaibhav Jain, Jilin Tian, Xiao-Ping Zhong, Huaxin Sheng, Wei Yang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-08-01
Edice:	Genome Medicine
Témata:	scRNA-seq CD45 high Stat1 Female Microglia-to-macrophage
On-line přístup:	https://doi.org/10.1186/s13073-024-01368-7
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