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Adipose-derived MSC extracellular vesicles ameliorate sepsis by reprogramming macrophages via miR-21-5p targeting PELI1

Sepsis is a common and life-threatening condition encountered in intensive care units (ICUs). Mesenchymal stromal cells (MSCs) and their small extracellular vesicles (EVs) have emerged as promising nanotherapeutics, particularly in the context of COVID-19. This study evaluates the efficacy and mech...

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Principais autores: Guannan Zhou, Jieqiong Song, Lizhen Xuan, Zhunyong Gu, Yimei Liu, Cheng Xu, Hongyu He
Format: Artigo
Sprog:Inglês
Udgivet: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2025-10-01
Serier:Biomolecules & Biomedicine
Fag:
ADMSCs
extracellular vesicles
EVs
sepsis
macrophages
IL-10
Online adgang:https://www.bjbms.org/ojs/index.php/bjbms/article/view/11971
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