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Astragaloside IV mitigates T-2 toxin-induced cytotoxicity by preserving mitochondrial homeostasis and suppressing apoptosis

T-2 toxin, a type A trichothecene mycotoxin, induces severe cytotoxicity primarily through mitochondrial dysfunction and apoptosis. In this study, the protective role of astragaloside IV (AS-IV) against T-2 toxin-induced damage was investigated using the human hepatoma cell line HepG2 as an in vitro...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Peixuan Li, Zhaojie Liu, Jia Yan, Haihua Huo, Yanchen Liu, Siqun Wan, Lu Guan, Feiyang Chen, Qingmei Chen, Jikai Wen, Yiqun Deng, Peiqiang Mu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2026-06-01
Schriftenreihe:Ecotoxicology and Environmental Safety
Schlagworte:
Astragaloside Ⅳ
T-2 toxin
Mitochondrial dysfunction
Apoptosis
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S0147651326005579
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