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Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2.

The switch between latency and the lytic cycle of Kaposi's sarcoma-associated herpesvirus (KSHV) is controlled by the expression of virally encoded ORF50 protein. Thus far, the regulatory mechanism underlying the protein stability of ORF50 is unknown. Our earlier studies have demonstrated that a pro...

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Principais autores: Tzu-Hsuan Chang, Shie-Shan Wang, Lee-Wen Chen, Ying-Ju Shih, Li-Kwan Chang, Shih-Tung Liu, Pey-Jium Chang
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2016-10-01
Series:PLoS Pathogens
Acceso en liña:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005918&type=printable
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