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Epigenetics, DNA damage, and aging

Over the course of a human lifespan, genome integrity erodes, leading to an increased abundance of several types of chromatin changes. The abundance of DNA lesions (chemical perturbations to nucleotides) increases with age, as does the number of genomic mutations and transcriptional disruptions caus...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Carolina Soto-Palma, Laura J. Niedernhofer, Christopher D. Faulk, Xiao Dong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2022-08-01
Saila:The Journal of Clinical Investigation
Sarrera elektronikoa:https://doi.org/10.1172/JCI158446
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